About Us
Revolutionizing
Cell & Gene Therapy
Through Innovation
Mission
& Vision
At Comprehensive Cell Solutions (CCS), we are redefining cGMP manufacturing for cell and gene therapies (CGT) through a transformative social enterprise model. With a foundation built on over 20 years of innovation at New York Blood Center Enterprises, CCS has become a leader in cell sourcing, processing, and manufacturing for regenerative medicine. Our expertise in hematopoietic stem cells (HSCs), cord blood-derived stem cells, and both autologous and allogeneic therapies makes us a trusted partner in advancing next-generation cell therapies.
We are driven by two core principles:
- Nurturing Innovation: Providing critical manufacturing capacity and cell-sourcing solutions to early-stage developers of advanced therapies, supporting pre-clinical assets, early-phase assets, and Phase I-II clinical manufacturing.
- Strengthening Public Health: Leveraging our revenues to directly support life-saving blood operations, regenerative medicine research, and innovative initiatives that impact millions worldwide.
When you partner with CCS, you not only gain access to a team focused on world-class cell therapy manufacturing and phase-appropriate development support, but also support a mission that serves 75 million people annually through the supply of blood products, testing services, research and innovation.
As part of New York Blood Center Enterprises (NYBCe), a mission-driven nonprofit enterprise, CCS combines scientific excellence, scalable cell therapy solutions, client-focused strategies and patient/donor-centric care with a commitment to global health. While other manufacturers may offer similar services, CCS stands apart – here, science meets humanity to create therapies that transform and improve lives.
Across our organization, we are committed
to living our Enterprise Core Values
Integrity
Innovation
Quality
Excellence
Exemplary Service
Respect
Leadership
& Team
At CCS, our leadership team is composed of industry pioneers with deep expertise in CGT academic partnerships, stem cell technology, and GMP manufacturing. With backgrounds in pharmaceutical operations, process development, and cell therapy manufacturing, our leaders bring decades of experience in scalable cell therapy solutions, process validation, and regulatory compliance and technology transfer.
From overseeing multi-site GMP manufacturing to advancing technology transfer strategies, our experts work collaboratively to discover, develop, and meet the needs of academic researchers, emerging biotech firms, and global pharmaceutical companies. We are committed to transforming advanced cell engineering into life-changing therapies, ensuring that every project benefits from our precision, scalability, and quality-driven approach.
Thus, at CCS, our people are our greatest asset, driving next-generation cell therapies and pioneering innovative solutions for regenerative medicine.
Leadership:
Jo Anne Valentino, MS
Senior Vice President, CCS
Rawlinson Isaac, MPA
Vice President Cell Sourcing & Clinical Apheresis
Manlio Narici, MBA
Executive Director, Business Operations
Ayanna Bryan, PhD
Senior Director & Site Head, CCS NY & Senior Program Director NCBP
Omar F. Baez
Senior Director GMP Cell & Gene Manufacturing and Site Head
Rubina Pal, PhD, SCYM (ASCPi)
Senior Director, Process and Analytical Development, Site Head
Joseph Dwyer
Senior Director, Head of Quality Control
Betsy W. Jett
Senior Vice President, Quality/Regulatory Affairs
Andi Baggarley, MSHA MT(ASCP)
Director of Project Management
Dr. Patricia Shi, MD
VP at NYBC & Medical Director of CCS, Cellular Therapy Collections, Cellular Therapy Processing & NCBP
Christian Rouldan
Senior Director of Business Development
Our Commercial Team:
Jo Anne Valentino, MS
Senior Vice President, CCS
Rawlinson Isaac, MPA
Vice President Cell Sourcing & Clinical Apheresis
Manlio Narici, MBA
Executive Director, Business Operations
Ayanna Bryan, PhD
Senior Director & Site Head, CCS NY & Senior Program Director NCBP
Omar F. Baez
Senior Director GMP Cell & Gene Manufacturing and Site Head
Rubina Pal, PhD, SCYM (ASCPi)
Senior Director, Process and Analytical Development, Site Head
Joseph Dwyer
Senior Director, Head of Quality Control
Betsy W. Jett
Senior Vice President, Quality/Regulatory Affairs
Andi Baggarley, MSHA MT(ASCP)
Director of Project Management
Dr. Patricia Shi, MD
VP at NYBC & Medical Director of CCS, Cellular Therapy Collections, Cellular Therapy Processing & NCBP
Christian Rouldan
Senior Director of Business Development
Testimonials
Dendreon and CCS have collaborated for over a decade, with NYBC serving as a trusted apheresis partner. They provide comprehensive vein assessment services, which are a key component of the Provenge® treatment process. These services not only help familiarize patients with the staff and the collection center but also offer them an opportunity to ask questions and learn more about the apheresis procedure.
Additionally, Dendreon and CCS have continued to partner in setting up apheresis collection centers to further support the Provenge® treatment process. Having worked closely with the CCS team on a variety of initiatives, I can confidently say that they are dedicated, patient-focused, and committed to excellence.
Locations
With strategically placed CGT manufacturing and cell collection sites, CCS delivers cellular starting material, process and analytical development, and cryopreservation services with unmatched efficiency and accessibility.
- New York, NY: Flagship location for cell sourcing, stem cell technology, and cord blood-derived stem cells.
- Houston, TX: Process development and analytical testing hub, supporting early-phase assets and pre-clinical assets.
- Louisville, KY: Core facility supporting apheresis and cell sourcing through GMP manufacturing and contract testing with specialization in Phase I-II clinical manufacturing of autologous and allogenic cell therapies in the heart of the US.
With our Draw-to-Thaw™ solutions and seamless technology transfer process, CCS ensures efficient logistics and scalable cell therapy solutions to meet your needs.
Licenses, Permits & Certifications
Careers
Join CCS and be part of a mission-driven team advancing cell and gene therapies while improving global health. Our team is growing, and we are actively seeking qualified candidates for key roles in Rye, NY, and Louisville, KY.
All job opportunities at CCS are managed through NYBC Enterprise, ensuring a commitment to excellence, innovation, and maximizing patient impact.
Click on a position below to view details and apply directly through the NYBCe hiring portal. Explore open positions today and help us develop life-saving therapies, drive biotech innovation, and shape the future of medicine.
Technologist – Cellular Therapy
Location: Rye, NY
Process and cryopreserve cell therapy products, conduct cell enumeration, perform quality control, and ensure compliance with laboratory standards and regulations.
Cellular Therapy Processing Technician-I
Location: Rye, NY
Process and cryopreserve hematopoietic progenitor cells, perform viability testing, ensure regulatory compliance, and manage lab inventory and documentation.
RN: Therapeutic Apheresis I-RNs Full Time
Location: Rye, NY
Perform therapeutic and cellular apheresis procedures, assess patients, administer blood products and medications, and ensure compliance with clinical protocols in a mobile setting.
Vice President, Quality & Regulatory Affairs
Location: Rye, NY
Oversee quality and regulatory affairs for cell therapy manufacturing, ensuring compliance, managing FDA submissions, and leading strategic quality initiatives.
Executive Director, Regional Quality and Regulatory Affairs
Location: Louisville, KY
Lead regional quality and regulatory initiatives for cell therapy manufacturing, ensuring compliance, managing FDA submissions, and overseeing quality systems.
RN Therapeutic Apheresis I
Location: NY
As a Registered Nurse in Therapeutic/Cellular Apheresis, you will be responsible for performing therapeutic and cellular apheresis procedures for both adult and pediatric patients in a mobile setting.